ADF/Cofilin-Mediated Actin Retrograde Flow Directs Neurite Formation in the Developing Brain
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ADF/Cofilin-Mediated Actin Retrograde Flow Directs Neurite Formation in the Developing Brain
Neurites are the characteristic structural element of neurons that will initiate brain connectivity and elaborate information. Early in development, neurons are spherical cells but this symmetry is broken through the initial formation of neurites. This fundamental step is thought to rely on actin and microtubule dynamics. However, it is unclear which aspects of the complex actin behavior contro...
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ژورنال
عنوان ژورنال: Neuron
سال: 2012
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2012.09.038